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Theorem (Diophantine Equation With No Solutions)
The equation  
\[x^4+y^4=z^2\]
  has no integer solutions.
Proof
Suppose  
\[x_1, \; y_1, \; z_1 \]
  is a solution. Suppose  
\[gcd(x, \; y)=d \gt 1\]
  then  
\[x^4+y^4=z^2 \rightarrow (dx')^4+(yd')^4=z^2 \rightarrow d^2 | z\]
  and  
\[gcd(x', \; y' )=1\]
. We can assume therefore that  
\[gcd(x', \; y' )=1\]
. By writing the equation as  
\[(x_1^2)^2+(y_1^2)^2=z_1^2\]
. (Pythagoras) we can take  
\[x_1^2, \; y_1^2, \; z_1\]
  as Pythagorean Triples,  
\[x_1=2mn,, y^2_1=m^2-n^2\]
, where  
\[gcd(m, \; n)=1, \; m \gt n /gt 0\]
, and  
\[m, \; n\]
  have opposite polarity.  
\[m, \; n\]
  must be odd and even respectively since if the other way round then  
\[(2k)^2-(2j+1)^2=4k^2-4j^2-4j-1 \equiv 3 \; (mod \; 4)\]
  but any square number is equal to 0 or 1 modulo 4.
Putting  
\[m=2r\]
  the equation for  
\[x_1\]
  becomes  
\[\( \frac{x_1}{2} \)^2=mr\]
  where  
\[m\]
  and  
\[r= \frac{n}{2}\]
  are relatively prime, hence  
\[m, \; r\]
  are both square numbers. Put  
\[m=s^2, \; r=t^2\]
>
From the equation  
\[y_2^2=m^2-n^2\]
   
\[(y_1, \; m, \; n)\]
  is a Pythagorean triple so  
\[n=2uv, \; y_1=u^2-v^2, \; m=u^2+v^2\]
 where  
\[u, \; v\]
  are relatively prime integers off opposite polarity with  
\[u \gt v\]
.
Now  
\[n=2r=2t^2\]
  so the first of these equations becomes  
\[uv=t^2\]
. It follows that  
\[u, \; v\]
  are each square numbers say  
\[u=x_2^2, v=y_2^2\]
  and substituting into  
\[m=u^2+v^2\]
  gives  
\[x^2_2+y^2_2=m=s^2 \; ({}=z^2_2)\]
  say. This solution satisfies  
\[0 \lt z_2=s \le m \lt m^2+n^2=z_1\]
.
Hence a smaller solution exists, which is impossible and the proof is complete.